Mutations for Yield and Protein Increase

Tech ID: 16.613

Key Features

  • UPL3 genome editing for yield increase in crops
  • Down regulation of UPL3 increases seed yield, protein and lipid in content
  • New: homologues identified in monocot crops


Down regulation of UPL3 leads to increases in seed yield and seed protein and lipid content.  Single homologues have now been identified as gene editing targets in monocot crops (maize, wheat, rice and barley) and also cotton.  Further analysis of elite oil seed rape germplasm shows that there is still potential to increase yields through down regulation of UPL3.

For further detailed information please download the non-confidential summary pdf.


Published: WO/2018/130828

Granted: US 11,473,097


Not yet published in the scientific literature.

Contact: Dr Lars von Borcke

Charlotte Miller and Mike Bevan
John Innes Centre (Norwich, UK)