Tech ID: 17.624
Xiangdong Fu and colleagues at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing have found that a growth-regulating factor (GRF4) interacts directly with the DELLA growth inhibitor and this interaction confers homoeostatic co-regulation of carbon/nitrogen balance. While GRF4 promotes and integrates C-fixation, N-assimilation and cell proliferation, DELLA inhibits them. Increased GRF4 abundance favours increased C and N assimilation without loss of yield-enhancing dwarfism. This opens the way to increase the N-use/efficiency of high yielding crops, resulting in major economic and environmental advantages. A range of approaches are possible, including genome editing, and in a range of crop species.
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Published: WO/2019/158911; EP 3751990; CN 111818794A; US 20210071191 A1
Li et al (2018). Modulating plant growth–metabolism coordination for sustainable agriculture. Nature; 560: 595–600. https://doi.org/10.1038/s41586-018-0415-5