02.301 - The Dynamic Gastric Model and The Model Gut
Patent Reference: International Patent Publication No. WO/2007/010238. US Patents 8,092,222 & 8,435,036. Australian Patent 2006271423. European Patent 1,907,108.
The Dynamic Gastric Model
The Dynamic Gastric Model (DGM) is a "state of the art" in-vitro system that simulates human gastric digestion, developed at the Institute of Food Research (IFR). The DGM is the first known in-vitro model developed to combine emerging scientific knowledge of the physical, mechanical and biochemical environments experienced by the luminal contents of the human stomach, in a single predictive system.
The Model Gut
The Model Gut is a business unit of PBL, established to provide contract research and development services to the Food and Pharmaceutical industries. Utilising the ground-breaking DGM, the Model Gut provides bio-relevant testing of oral pharmaceutical formulations and novel food structures and products. The Model Gut business was established as a collaboration between PBL and IFR, operating as a fully commercial entity but integrated with the gut-modelling group within IFR. The recent transfer of business to the Danish CRO Bioneer A/S provides the Model Gut with a step-change in its capacity to delivery a full-service offering, integrating its proprietary gut simulations with full analytical backup.
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